Ison's high inclination to the ecliptic (62 degrees) is what keeps it in Cancer.
This is also very close to the inclination of our Galactic Equator (60 degrees).

What does this mean? Cancer is the sign of home, family, emotions, nurturing, security, and the past. I've always felt that humanity was very Cancerian-like in nature always dominated by the need for security and survival. but there was no long-term influence or transit in the sky to reflect this (other than the star Sirius). Ison seems to fit the bill very well.

The orbit of Ison is based on a 2.15 year observation arc which may not be sufficient to peg its entire hyperbolic orbit which is still in question. The astronomers give it millions of years but I feel it is much less than that -perhaps in the hundreds of years. I feel astronomy has a way of exaggerating its distances and time periods.

Also, EVERY object in the heavens has deep spiritual, social, and even mundane significance, something modern astronomy tends to ignore or downplay. The current rift between science and the occult or spirituality is artificial and desperately needs to be healed. What Ison actually represents is unknown, but like all comets, it is a messenger of some sort, portending important cycles and events. Perhaps Ison in Cancer means 'I the Son am the Preserver' (Cancer).

Below are tables of Ison's position in the tropical zodiac from 1600 to 2500 AD. Most of us living today have Ison at 18 to 24 degrees of Cancer,